Wednesday, May 07, 2025

  • Wednesday, May 07, 2025
  • Elder of Ziyon
This press release by Hebrew University was published in Medical Xpress:
Researchers at the Hebrew University of Jerusalem and the IDF Medical Corps have discovered a promising new therapeutic approach to treating hemorrhagic shock, a life-threatening condition caused by severe blood loss that remains the leading cause of preventable death in trauma cases globally.

The study, led by Dr. Ariel Furer and Dr. Maya Simchoni, from the Institute for Research in Military Medicine, a joint project between Hebrew University-Hadassah Medical School and the Israel Defense Forces (IDF) Medical Corps, demonstrates that activating Protein Kinase C epsilon (PKC-ε) significantly improves early survival rates and physiological stability following severe hemorrhage.

The work is published in the journal Scientific Reports.

In a carefully controlled experiment using a porcine model, researchers induced hemorrhagic shock by withdrawing 35% of the animals' total blood volume.

Animals treated with a PKC-ε activator peptide just five minutes after the onset of bleeding showed dramatically improved survival—73% of treated subjects survived compared to only 25% of those left untreated. Additionally, treated animals maintained significantly better cardiovascular stability, including blood pressure, heart rate, and cardiac output, all critical indicators of effective response during severe trauma.

It has not yet been tested on people, but for BDSers, here is a card they can print out to keep in their wallets in case they find themselves with massive blood loss:

 


(h/t Irene)



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