Wednesday, October 06, 2004

  • Wednesday, October 06, 2004
  • Elder of Ziyon

STOCKHOLM, Sweden - Israelis Aaron Ciechanover and Avram Hershko and American Irwin Rose won the 2004 Nobel Prize in chemistry Wednesday for discovering a key way cells destroy unwanted proteins — starting with a chemical "kiss of death."


Their work provides the basis for developing new therapies for diseases such as cervical cancer and cystic fibrosis.

The Royal Swedish Academy of Sciences honored Ciechanover, 57, Hershko, 67, and Rose, 78, for work they did in the late 1970s and early 1980s.

Each human cell contains about 100,000 different proteins, busy bees that carry out jobs like speeding up chemical reactions and acting as signals. At least five Nobel prizes have been given for research into how cells make proteins, but the question of how they destroy proteins has received much less attention, the assembly said.

The three scientists uncovered a process that starts when a doomed protein is grabbed by a particular molecule, marking it for destruction. Such marked proteins are then chopped to pieces.

The process governs such key processes as cell division, DNA repair and quality control of newly produced proteins, as well as important parts of the body's immune defenses against disease, the academy said in its citation.

Scientists are trying to use the process to create medicines, either to prevent the breakdown of proteins or make the cell destroy disease-causing ones. One example is the cancer drug Velcade, approved last year in the United States, which interferes with the cell's protein-chopping machine.

Many other drugs that harness the protein-destroying process are in development, said Ciechanover, who is director of the Rappaport Family Institute for Research in Medical Sciences at the Technion, in Haifa, Israel. Hershko, originally from Hungary, is a professor there.

Rose is a specialist at the department of physiology and biophysics at the college of medicine at the University of California, Irvine.

Ciechanover told reporters, "I'm happy that I can speak on the phone at all and that I remember I my English. I'm not myself, that's for sure, not for a while."

It's the first time an Israeli has won a Nobel science prize, although Israelis have won peace and literature Nobels. "I am as proud for myself as I am for my country," Ciechanover said.

The prizes, which include a $1.3 million check, a gold medal and a diploma, are presented on Dec. 10, the anniversary of Nobel's death in 1896.

EoZTV Podcast

Podcast URL

Subscribe in podnovaSubscribe with FeedlyAdd to netvibes
addtomyyahoo4Subscribe with SubToMe

follow me

search eoz

Loading...

Recent posts from other blogs

comments

Speaking

Follow by Email

Contact

elder -at- elderofziyon dot com

translate

E-Book

For $18 donation








Sample Text

EoZ's Most Popular Posts Ever

Hasbys!

Elder of Ziyon - حـكـيـم صـهـيـون

Elder of Ziyon - حـكـيـم صـهـيـون
This blog may be a labor of love for me, but it takes a lot of effort, time and money. For over 11 years and over 23,000 articles I have been providing accurate, original news that would have remained unnoticed. I've written hundreds of scoops and sometimes my reporting ends up making a real difference. I appreciate any donations you can give to keep this blog going.

Donate!

Monthly subscription:
Payment options

One time donation:

Tweets

Compliments

The Jerusalem Report:"A seemingly indefatigable one-man operation, armed only with a computer, chutzpa and stamina."

Algemeiner: "Fiercely intelligent and erudite"

Omri: "Elder is one of the best established and most respected members of the jblogosphere..."
Atheist Jew:"Elder of Ziyon probably had the greatest impression on me..."
Soccer Dad: "He undertakes the important task of making sure that his readers learn from history."
AbbaGav: "A truly exceptional blog..."
Judeopundit: "[A] venerable blog-pioneer and beloved patriarchal figure...his blog is indispensable."
Oleh Musings: "The most comprehensive Zionist blog I have seen."
Carl in Jerusalem: "...probably the most under-recognized blog in the JBlogsphere as far as I am concerned."
Aussie Dave: "King of the auto-translation."
The Israel Situation:The Elder manages to write so many great, investigative posts that I am often looking to him for important news on the PalArab (his term for Palestinian Arab) side of things."
Tikun Olam: "Either you are carelessly ignorant or a willful liar and distorter of the truth. Either way, it makes you one mean SOB."
Mondoweiss commenter: "For virulent pro-Zionism (and plain straightforward lies of course) there is nothing much to beat it."
Didi Remez: "Leading wingnut"

Interesting Blogs

Categories

Abbas liar Academic fraud administrivia al-Qaeda algeria American Jews Amnesty analysis anti-semitism apartheid arab refugees Arafat archaeology art ASHREI B'tselem bahrain bbc BDS BDSFail Bedouin Beitunia beoz book review breaking the silence Cardozo Chanukah Christians conspiracy theories Cyprus Daphne Anson Davis report DCI-P double standards Egypt Elder gets results ElderToons Electronic Intifada EoZNews eoztv Erekat EU Euro-Mid Observer Fake Civilians 2014 Fatah featured fisking flotilla free gaza freedom of press palestinian style future martyr gaza Gaza Platform George Galloway gideon levy gilad shalit gisha Goldstone Report Good news Grapel Guardian gunness hamas Hamas war crimes hasbara Hasby 2014 Hasby 2016 Hebron helen thomas hezbollah history Hizballah Holocaust denial honor killing HRW Human Rights Humanitarian crisis humor Hypocrisy ICRC Ilan Pappe impossible peace incitement international law intransigence iran Iraq Islamism Israel Loves America Israeli culture Israeli high-tech J Street jabalya jeremy bowen Jerusalem jewish fiction Jewish Voice for Peace jihad jimmy carter John Kerry jokes jonathan cook Jordan Juan Cole Judea-Samaria Kairos Karl Vick ken roth khalid amayreh Khaybar Lebanon leftists Linkdump lumish mahmoud zahar Malaysia max blumenthal McGraw-Hill media bias Methodist Miftah Mohammed Assaf Mondoweiss moonbats music Muslim Brotherhood Nakba Natural gas Nazi NGO NIF norpac NYT Occupation offbeat oxfam PA corruption PalArab lies Palestine Papers pallywood pchr PCUSA Peter Beinart poll Poster Preoccupied Prisoners propaganda Proud to be Zionist purimshpiel Qaradawi Qassam calendar Rafah Ray Hanania real liberals reference Richard Falk rogel alpher roger cohen roger waters Saudi Arabia saudi vice self-death self-death palestinians sex crimes SFSU shechita sheikh tamimi Shujaiyeh SodaStream South Africa Speech stamps Syria Tarabin Temple Mount Terrorism This is Zionism Thomas Friedman Tunisia Turkey UCI UK UN unesco unhrc United Arab Emirates Unity unrwa UNRWA hate unrwa reports UNRWA-USA Vic Rosenthal Washington wikileaks work accident X-washing Yemen zahran zionist attack zoo Zvi

Blog Archive

subscribe via email